Discussions

PSA (polysialic acid) is found on the surface of a variety of cells, including mammalian cells; thus, it is a biocompatible and biodegradable natural polymer that is highly hydrophilic and has no identified receptors in the body.
The prolonged residence of polysialylated conjugates increases the species' potential to reach its target and provide a therapeutic effect before being cleared from circulation, thereby extending the duration of action. We are an innovative, experienced provider of polysialylation half-life extension drug development solutions. We use our state-of-the-art R&D and manufacturing expertise to help our customers develop stand-out products.